nickwitha_k (he/him)

  • 2 Posts
  • 428 Comments
Joined 1 year ago
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Cake day: July 16th, 2023

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  • I maintained a CEPH cluster a few years back. I can verify that speeds under 10GbE will cause a lot of weird issues. Ideally, you’ll even want a dedicated 10GbE purely for CEPH to do its automatic maintenance stuff and not impact storage clients.

    The PGs is a separate issue. Each PG is like a disk partition. There’s some funky math and guidelines to calculate the ideal number for each pool, based upon disks, OSDs, capacity, replicas, etc. Basically, more PGs means that there are more (but smaller) places for CEPH to store data. This means that balancing over a larger number of nodes and drives is easier. It also means that there’s more metadata to track. So, really, it’s a bit of a balancing act.









  • …I’m left with a strong inconclusive as to whether it’s possible :(

    Possible, yes. Possible with current technology and understanding, no.

    The methylation of DNA and other ways that its functionality is modified is something that is studied in epigenetics. Such modifications can also be carriers of heritable traits (ex. a study on Icelandic families found that experiencing famine could change the likelihood of diabetes two generations later). Modifying methylation has also been investigated for treatment of genetic diseases.

    Conceivably, epigenome editing could be used to modify the sperm/egg methylation to make them compatible. But, that’s probably a ways a way from being practical.