I bought a National Instrument’s data acquisition card (PCIe-6535B) not knowing that National Instruments is not very Linux-friendly and I was not able to get it working. At least it was a used card so I did not pay to much for it, but I learned my lesson not to assume compatibility.

Once I also used ‘rm -rvf *’ from my home directory while SSH’d into a supercomputer (I made a syntax error when trying to cd into the folder that I actually wanted to delete). I was able to get my data restored from a backup, but sending that e-mail was a bit embarrassing 😆

Wow, a really nice shot of a really nice frog!

Thanks a lot for looking into this!

While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.

I am not super familiar with the topic, but I have been told of some successful animal studies on implanting the organoid tissue into the animals from which the stem cells were derived.

This other article from 2013 lists a few concerns, and I think this is the closest to what you were looking for: https://pmc.ncbi.nlm.nih.gov/articles/PMC3931018/#sec3

Yeah, that covers nicely what I was wondering about. Especially the reason 1 (embryonic proteins not present during immune system education) and reason 2 (epigenetic changes). I can appreciate that these mechanisms might possibly cause issues, but I would be curious to learn the actual magnitude of their impact.

Yamanaka named iPSCs with a lower case “i” due to the popularity of the iPod and other products.

Oooh, that’s why! I do think iPSC looks nicer than IPSC. Not a big apple fan, though

Always exciting to learn about new perspectives on consciousness!

I have searched for the “Cellular Basis of Consciousness (CBC)” theory and I do not personally find it very compelling. I appreciate that the hard problem of consciousness is very difficult to address using the scientific method, but I suspect that consciousness arises from a form of processing that requires computations of the kind performed by animal brains. I don’t think that the kind of biophysics that allows cells to sense and respond to the environment are enough to create a conscious experience.

About the: “third state”. Cells are alive, independently of the multi-cellular organism that they come from. I don’t agree that changing the way that the cells are organized constitutes some “third state”.

Despite my disagreements, it is still nice to read and think about. Thanks for sharing.

Interesting! I wonder if it is already technically feasible to culture tooth-like pieces from the patient’s stem cells. Instead of extracting and carving a tooth, it would be cool to grow the tissue in some kind of structured 3D matrix. Patient gets to keep their canine then.

That said… Do you know if tissue grown from a patient’s own stem cells is generally not rejected by the immune system? I am not sure if cells need to differentiate within the body to get labeled by some molecular markers that make them immunocompatible, or if having the same genetic makeup is good enough.

Ooh, cool! 😁 That detector seems to be working only in “Geiger mode”, which means that it can count the number of X-rays/Gamma particles but it does not estimate their energy. So, the dedicated devices are still better in that they allow you to identify the source of the radiation by measuring the counts and the energy distribution simultaneously.

It probably would not be too difficult to build the open gamma detector into something like a pinephone. I don’t think that has been done yet.

My experience with phone zoom has been underwhelming so far, but I would like to check out the Samsung S2x’s 10x zoom when I have the chance!

Still, I really like using binoculars because they transport me next to what I am looking at and do so in very high definition. I do have >100€ binoculars though, colors look very nice through them. I think it will be difficult to replicate via a screen.

Yes. The camera pixels generate a current in response to light. You can add some filters to block certain wavelengths of light (like UV) from getting to the camera sensor, and tune the pixels so that they respond more to to specific colors. But X-rays and gamma rays can just pass through the filter. Often they will pass through sensor as well, but, in the cases that they do get absorbed by the sensor, they can also produce a current that to the camera’s readout electronics looks like other light would.

The gamma detectors I mentioned are very very sensitive. They respond to single X-ray/Gamma ray particles. These detectors can count how many individual particles collide with a small crystal cube every second. These crystals are special in that they produce a very tiny flash of light when an X-ray or gamma particle collides with them. As an added bonus, these sensors can directly measure the energy of the particles by measuring the strength of the flash, and from this information they can construct not only the total counts but also a spectrum. With this extreme sensitivity these detectors can measure small quantities of radiation that come from space, from rocks, and from other materials.

I looked for a video of a phone going through an X-ray machine, and found these:

https://www.youtube.com/watch?v=E8iSoPhtY3s

https://www.youtube.com/watch?v=V1YaroH6lHA

The white specks that you can see near second 25 (first video) and second 34 (second video) could be a result of the X-rays. I am not sure, but it seems reasonable to me. On contrast, when I put my radiacode through the X-ray machine in the airport the radiacode reacts very strongly and becomes saturated.

Radiation detectors. Such as the Radiacode or the Open Gamma Detector.

Binoculars are quite portable, very useful, and phones don’t do a good job at zooming in like that.

Smart watches integrate with phones but the phones by themselves are not so good at measuring the heart rate and other parameters directly.

Mini projectors. UV flashlights. Tools in general… There is so much actually. What type of gadgets are you looking for?

I find it strange that they are out-bidding each other like this when there are over 8 days left. I am not too experienced with bidding, but I thought that the normal strategy was to maybe place a placeholder bid if there is no activity, but more generally one waits until the last second to set a reasonably high bid. Going on a 1v1 with fast out-bidding over a week early seems bad for everyone except the seller. Perhaps someone can explain.

Even though:

These data are associative and do not establish a causal role for such particles affecting health

I still don’t feel so nonchalant about the idea of microplastics lodging on my brain. While the effect on human brains is very difficult to directly measure, we do have a lot of data on mice that suggest that having plastic in the brain is bad for the brain.

When quickly looking into EU food regulations it seems like microplastic content is not regulated in food, and the logic appears to be along the lines that not enough data is available to assess the actual risk. This makes some sense in that measurement, control, and enforcing limits is likely to be difficult, expensive, and might create some economic challenges, and so regulators might not want to go this route unless proven absolutely necessary.

At the same time, data does exist showing that the plastic levels are increasing in our brains, and we have very good reasons to believe that this is not a good thing. It is not that we are completely in the dark - I am sure some smart people would be able to come up with reasonable limits and methods of control by now.

My not-very-informed suspicion is that there is pressure from wealthy and powerful lobbyists that would significantly suffer from microplastics regulations, because ‘plastic in the brain’ has seemed like an obvious thing to address for some years now.

I have never been educated about how to avoid ingesting / breathing microplastics. Do any of you know some habits or diets that reduce or increase exposure to microplastics?

I think that panspermia is the most likely hypothesis to be eventually proven correct.

According to this hypothesis, very simple “living” structures can be found throughout space, scattered around planets, meteorites, and perhaps even in space dust. This dust can be thought of as fungal spores. When they land in a planet with suitable conditions, these systems can evolve into more complex life forms.

The alternatives to panspermia generally imply that Earth is a super special planet in which certain special conditions conspired at a point in time to allow an extremely unlikely event to happen. Panspermia suggests that, instead of a being a statistical anomaly, life is probably rather common throughout the universe.

I don’t have any recommendations, unfortunately. But this is very interesting! I have gotten into software-defined radio recently and radio astronomy seems like a good direction to continue learning. Hopefully someone has some good advice.

Ooooh, fascinating!

Thanks!

I have been away for some weeks for holidays. Has this happened often?

Check in your settings whether you have disabled the visibility of bot responses. This can happen if bots replied to you and your settings are set to not see them.

I find it satisfying to see the graph come down :)

Yes, sorry, there was some serious lagg in fetching posts from Lemmy World that persisted for several days and accumulated a 1-week delay.

But after upgrading Mander it is now fetching data from LW quite rapidly and it should be back in-sync in about a day and a half from now.

If you are curious about the ranking algorithm, there is some info here: https://join-lemmy.org/docs/contributors/07-ranking-algo.html

Awesome! The one with the sustained source loop is my favorite:

Also, the one that shoots out flames paints a picture similar to how a synchrotron behaves, shooting out X-rays into the beamlines as the electron bunches move around.

Upon looking into it closer, the synchrotron is a bit of a mixture of those two concepts - the source loop (booster ring) that is fed by the linear accelerator, and then the larger loop (storage room) that feeds X-rays the beamlines. Of course, many details differ, but still it is interesting to notice the similarities !